effect of lysozyme in maintenance medium for fl cells infected with para-influenza 3 virus
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Influenza virus uncoating in infected cells and effect of rimantadine.
Uncoating of influenza virus (strain WSN) in MDCK cells was studied by following the fate of the virus labelled with radioactive precursors. The accumulation of subviral components of input virus was observed in nuclear-associated cytoplasm (NAC) obtained by treatment of the nuclei with citric acid. Two types of subviral components were found there, ribonucleoproteins (RNPs) and larger subviral...
متن کاملRibonucleic acid synthesis in cells infected with influenza virus.
Virus-specific ribonucleic acid (RNA), synthesized in influenza virus-infected cells from 3.5 to 7.5 hr after infection, was studied. After velocity centrifugation in sucrose, three peaks of virus-specific RNA could be identified: 34S, 18S, and 11S. These RNA species are predominantly single-stranded and consist of 90% viral (plus) and 10% complementary (minus) RNA strands. Most (75%) of the co...
متن کاملConcanavalin a and Influenza Virus Infected Cells
Treatment of host cells with Concanavalin A prevents the assembly or release of fowl plague virus from chick fibroblasts and inhibits fusion of BHK cells by the paramyxovirus SV5. Metabolic events of the host cells are not greatly impaired during the early phase of infection. There is evi dence that the carbohydrate moiety of the Con A receptor of fowl plague virus is associated with the viral ...
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archives of razi instituteجلد ۱۴، شماره ۱، صفحات ۶۷-۶۸
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